Villages, the villagers often are focused on eatin
Liu Ji, white mushrooms
open and his team (front row, second from the right to Liu Ji-opened)
30 years, almost every summer, death will come as some high ground in the rugged Yunnan Province small villages. When a peasant woman carrying a basket called Li Linmei of mushrooms, head of the path traversed Royal Village and saw a small cottage in front of a brand new white curtains hang, then she will know the village was being \
Wang Dali Village is a small village in the east,Coogi Jeans, away from Dali city about an hour. Every year, when the monsoon and the monsoon arrived here by the end of June, the village will have people of all ages die mysteriously one by one.
No one knows the \
Dr Li Guanghui village turned pale only come out from the hall. He frowned and said to himself: \
mysterious killer
in Wang Village and the surrounding area of similar deaths, should be called the \Since 1978, more than more than 400 cases of local deaths and dozens of cases of non-fatal heart disease cases are classified as such a \
like a curse, these \Therefore, when a man appeared at the village, other villagers will often lead to panic.
However, no one knows \50-year-old Li Linmei remember, from the late 70s of last century, the annual rainy season, there will be many experts came to Beijing from Kunming Shi, into the village of about 2000 meters above sea level. These city people always wear glasses, frowning, in a book and Tu Tu painting, and then one after another to leave.
2005 年 6 月, 中国 CDC epidemiologist, chief epidemiologist who led his team came to light in Dali, Yunnan. They and local experts in Yunnan Province, and began a period of 5 years follow-up work. The first step, they sudden death syndrome of these villages, including the Wang Village included, for the life assessment.
Prior to that, deputy director of Yunnan endemic disease prevention HUANG Wen Another team led by a cast of a large network. Since 2002, HUANG Wen-prepared for this syndrome in a long list of risk factors, including enterovirus infection above, drink from a mountain stream, alcohol abuse, and edible vegetable oil and mushrooms.
\Kunming Institute of Botany, Chinese Academy of Sciences he is the chief medicine experts, participated in the 5 years of investigation and evidence collection.
to catch the culprits, people tried their best. Initially, the Yunnan local experts tend to be the cause of death attributable to Keshan disease. In the rugged piece of high ground in northern Yunnan Province, the soil lacks selenium is a risk factor for Keshan disease.
this thesis was soon overthrown, Yunnan, researchers found only in four villages in the Coxsackie virus, which is Keshan disease leading to death of a fatal factor. In addition, patients with Keshan disease of heart muscle in the invasion by the Coxsackie virus, it will lead to organ damage. And nearly half of cardiac sudden death \
Not only that, Keshan disease, the chronic disease develops slowly, has never been to an outbreak of group. More critical is that collective ill patients,Calvin Klein Jeans, about 2 / 3 of cases occur in between unrelated villagers, so Keshan disease in which genetic factors play any role even more unlikely.
death was continuing. Open to hear the story of Liu Ji, \, has some strange symptoms can not even classified.
because nothing came of the investigation numerous times before, the villagers on the arrival of these experts have been accustomed to. Old rumors still circulating among the villagers. Older villagers would tell little children: June to August each year the rainy season, do not go in very late, or it will be \
However, death is not the only place in the night. Some villagers in the day talking with people, suddenly fell to the ground,Artful Dodger Jeans, the heart stops beating.
search for the killers
helpless in the experts when the mysterious \
2005 summer, Yunnan local researchers to have light and his team sent a group of cardiac pathology slides. Images from three families, which three families at the same time, both have two people dead.
all the evidence points to a fatal arrhythmia, there are indications that certain drugs or toxic substances similar to upset the balance of the heart. To confirm this idea, the experts ask for these dead to the hospital before he died of ECG, electrocardiogram confirmed the suspicion.
In addition, in 2006 and 2007 survey, the experts it was a huge discovery. Several families of the deceased in the home found a small white mushrooms. The other sudden death of several family members also admitted that the deceased had consumed this strange little mushrooms.
2008 in the summer, Liu Ji-opened to begin testing for toxicity of this little white mushroom.
the beginning, the senior medicine experts are not convinced that white mushrooms will be toxic. He and his team less than half a meter along a narrow path into the forest in northern Yunnan. Trees grow tall, the sun is almost impossible to come by lush foliage transmission. These small white mushrooms, grow in clusters on dead tree stump, like a little white flowers.
\When the white mushrooms picked from a tree stump, the color will become a faint light gray.
capture \
LIU Ji-kai and his team members to wear gloves and white mushroom that looks unusual dipped in alcohol. This particular experiment is often used alcohol in the chemical extraction. He dubbed this process \
After 1-3 days of \This extract is packed in the chemical containers, transported to the Chinese Academy of Medical Sciences in Beijing Institute of Laboratory Animal.
number of mice have been singled out robust, installed in the experimental cage. Extract was divided into different doses, as food, fed to the mice.
\
Surprisingly, in 24 hours, mice were dying one after another, no matter how many swallowed the dose. Before they died, were the emergence of a strange symptoms. They got epilepsy, as the same, constantly trembling, edema, intestinal bleeding.
proved poisonous white mushrooms.
Next, Liu Ji-opened to all extracts, to purify separation. He and his team, using a chromatographic technique to extract the removal of interfering substances, extracted from a toxic compound.
spectrum technology is also put to use. Liu Ji open electronic mass spectrometer to break the compound of the elements, use of spectroscopy in magnetic resonance imaging, stripping out the three kinds of \Such amino acids and usually contact the experts of 26 different amino acids.
general, most of the amino acid composition of proteins and their chemical structure has a fixed pattern, and the body’s metabolism plays an important role. However, extracted from a white mushroom of amino acids is, however, any of the proteins are unrelated. One of the amino acid structure or even the \
\He is almost ready to judge who patronize each village in Yunnan, \
sent packing killer
not all agree. Such as Li Guanghui.
He insisted that by toxic substances or pathogens Stream pollution is the main reason leading to this sudden death syndrome, \
villagers in the area like the mountains, natural drinking water, although the experts opinion, this water has a strange flavor stocks.
LIU Ji-kai also confirmed that not all of the sudden death of this little white mushrooms are edible. Investigation team of researchers noted that heavy metals seem to die during barium play a role. It can cause arrhythmias.
2006, the investigation team on the occurrence of sudden death in two groups of villages, the families of the deceased and blood samples were extracted. Many people have exceeded the barium content, which reached a dead level of high concentration. In another incident, a group of sudden death, the deceased’s blood, urine, hair and local water, are detected high levels of barium element.
In addition, some villagers sick or healthy ECG data, also targeting the element barium. It is noteworthy that white mushrooms barium index than the normal level.
had rejected the light of China Youth Daily reporters. He hesitated for a long time after that, \An unidentified expert said the investigation \
has often put into the baskets of Li Linmei the mushrooms and some villagers are unwilling to believe, is a small white mushrooms led to sudden death. In the small village of Yunnan highlands, the wild mushrooms are important sources of income. Mushroom picking season is usually in August each year between 7, \
Li Linmei and villagers often easy mushroom to put up tents in a row over the number of days. There will be some middlemen, carrying sacks and steelyard, will pick the mushrooms to the villagers to go low income. These plump, juicy mushrooms, brokers will be sold to restaurants or exported. Matsutake Japanese food on the table, the European hotels of the boletus, dried mushrooms, etc., mostly produced in Yunnan.
exception of small white mushrooms, because there is no commercial value, has become the only poor villagers willing to eat mushroom. Villagers can not say exactly the name of this mushroom, although they have lived in the village there for many years.
no matter what, a movement started. From June 2009, the Chinese Centre for Disease Control and Prevention experts and the Yunnan local researchers, in-depth into these isolated little village. They will be some health pamphlets distributed to the villagers, the above picture printed with this little white mushrooms, and marked with red in the pork on a skewer. Valley field loudspeakers began uninterrupted playback, to persuade the villagers not to eat that white mushrooms.
look, the devil for the time being were sent packing. LIU Ji-kai told the China Youth Daily reporter, had this information after the rainy season began in 2010, the village groups of cases of sudden death \Reporter Zhou Kaili
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